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Abstract:

Introduction: surgical treatment of an area of accumulation of breast microcalcifications requires the surgeon to choose the optimal method of surgery. For a long time, the gold standard of surgery was the placement of a wire needle under X-ray control and subsequent removal. In our study, we want to demonstrate one of new methods, which is based on the placement of ultrasound marks in the area of accumulation of calcifications at the preoperative stage and further removal under the control of ultrasound device.

Aim: was to make comparative analysis and estimate the effectiveness of preoperative marking with ultrasound-positive (US-positive) marks in patients with non-palpable breast neoplasms.

Material and methods: the study included 165 patients (age 32 - 71 years). Patients were divided into three groups depending on the preoperative marking. The first group: installed ultrasound-positive Gel Mark UltraCor Bard marks in the region of microcalcifications at the outpatient stage.

The second group: marking with a wire needle «DuaLok» Bard immediately before the operation.

The third group: according to results of a repeated preoperative examination, which included: unilateral mammography in two projections with marker, a skin mark was established in the projection of a non-palpable formation.

Results: study showed that when choosing a surgical treatment using ultrasound-positive marks, the risk of detecting tumor cells at edges of the resection decreases, the time of surgery is shortened, and the volume of resection of healthy breast tissue is minimized.

Study proved that marking using ultrasound-positive marks has an advantage over other methods of preoperative marking and can be implemented in medical organizations that are not equipped with x-ray equipment for marking non-palpable breast formations immediately before surgery.

 

References

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2.     World Health Organization. World health statistics 2019.

https://www.who.int/gho/publications/world_health_statistics/2019/EN_WHS_2019_Main.pdf?ua=1

3.     Kaprin AD, Starinsky VV, Petrova GV. Malignant neoplasms in Russia in 2018 (morbidity and mortality). - M.: MNII them. P.A. Herzen - branch of the Federal State Budgetary Institution Scientific Research Center for Radiology of the Ministry of Health of Russia, 2019; 250 [In Russ].

4.     Manuylova OO, Pavlova TV, Didenko VV, et al. Guidelines for the use of the BI-RADS system for mammography examination. Moscow. 2017; 23 [In Russ].

5.     American College of Radiology, ACR BI-RADS Atlas 5th Edition, 2013.

6.     Bonfiglio R, Scimeca M, Urbano N, et al. Breast microcalcifications: biological and diagnostic perspectives. Future Oncol. 2018; 14(30): 3097-3099.

7.     Tardioli S, Ballesio L, Gigli S, et al. Wire-guided Localization in Non-palpable Breast Cancer: Results from Monocentric Experience. Anticancer Res. 2016; 36(5): 2423-2427.

 

Abstract

The clinical case that is presented, demonstrates the need to sub-specialize radiologists in the field of mammology for a qualitative examination of the breast and timely diagnosis, including breast cancer. During last 8 years, the patient regularly (once every two years) underwent mammography in general-specialization medical facilities. According to findings of surveys conducted, nodal pathology of the breast was not identified. During the physical examination in the upper inner quadrant of the left mammary gland, a movable mass that was soldered to the skin up to 2.0 cm. When conducting a survey mammography in two standard projections in the lower inner quadrant of the left mammary gland, the nodal formation of the BIRADS 5 category was visualized. In a retrospective analysis of past mammograms, described above, nodal formation was noted on all presented mammographic images, the growth and changes in semiotic signs of the pathological focus were also observed. After additional diagnostic manipulations, a highly differentiated breast cancer with low mitotic activity was verified. 

 

References

1.     Kaprin A.D., Rozhkova N.I. National guidelines. Mammalogy. 2nd ed. M.: GEOTAR-Media. 2016; 496 [In Russ].

2.     Frantsuzova I.S. Analysis of risk factors for breast cancer. Mezhdunarodnyy nauchno-issledovatel'skiy zhurnal. 2019. -3 (81): 68-74 [In Russ].

3.     Chernaya A.V. Comparative analysis of informative value of digital mammography and mammoscintigraphy in breast cancer diagnostics. Dis. kand. med. nauk. SPb. 2018; 112. [In Russ].

4.     Vasil’ev A.Yu., Мanuylova О.О. Stereoscopic mammography. An alternative method for the breast cancer early diagnosis. Radiologiya-praktika. 2017.- 1(61): 6-14 [In Russ].

5.     Pavlova T.V., Vasil'ev A.Yu., Manuylova O.O. Method of сone-beam breast computed tomography (literature review). Radiologiya-praktika. 2019.-1(73): 21-27 [In Russ].

6.     Rozhkova N.I., Burdina I.I., Zapirova S.B., Kaprin A.D., Labazanova P.G., Mazo M.L., Mikushin S.Yu., Prokopenko S.P., Yakobs O.E. Areas of preventive work with the female population against breast cancer. Akademicheskiy zhurnal Zapadnoy Sibiri. 2019. Vol. 15.-2(79): 6-8 [In Russ].

7.     Visscher D.W. Sclerosingadenosis and risk of breast cancer / D. W. Visscher, A. Nassar, A. C. Degnim. Breast Cancer Res Treat. 2014. 144: 205-212.

8.     Pavlova T.V., Vasil'ev A.Yu., Manuylova O.O., Volobueva E.A. The impact of compliance with the rules of mammography laying on the timely diagnosis of breast cancer (the clinical example). Diagnosticheskaya i interventsionnaya radiologiya. 2019. -2 (13): 60-65 [In Russ].

9.     Shumakova T.A., Solntseva I.A., Safronova O.B., Savello V.E., Serebryakova S.V. The practical application of the international classification of Bi-RADS in mammology practice. Rukovodstvo dlya vrachey - SPb NII skoroy pomoshchi im. I.I.  Dzhanelidze. SPb. 2018; 217 [In Russ].

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